Publications

2020

Barbara Rendl - Lukas Janker - Fabian Kanz - Katharina Rebay-Salisbury Social Relations, Deprivation and Violence at Schleinbach, Lower Austria. Insights from an Interdisciplinary Analysis of the Early Bronze Age Human Remains page 13 doi: 10.1553/archaeologia104s13

Grunt, W.T.; Slany, A.; Semkova, M.; Colomer, R.; López-Rodríguez, M.L.; Wuczkowski, M.; Wagner, R.; Gerner, C.; Stübinger, G. Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors – a multi-omics analysis in ovarian cancer. Scientific Reports, 10, Article number: 14877 (2020) doi.org/10.1038/s41598-020-71491-z

Tchaikovsky, A.; Schoeberl, A.; Schueffl, H.; Raab, A.; Emin, S.; Slany, A.; Heffeter, P.; Koellensperger, G.; Swart, C. Quantification of ferritin-bound iron in murine samples for Alzheimer’s disease studies using species-specific isotope dilution mass spectrometry. Metrologia 57 (2020) 042101 (8pp); doi.org/10.1088/1681-7575/ab8c9f

Rebay-Salisbury, K., Janker, L., Pany-Kucera, D. et al. Child murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria. Archaeol Anthropol Sci 12, 265 (2020). doi.org/10.1007/s12520-020-01199-8

Del Favero, G.; Mayer, R.M.; Dellafiora, L.; Janker, L.; Niederstaetter, L.; Dall’Asta, C.; Gerner, C.; Marko, D. Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol. Cells 2020, 9(4), 847; doi.org/10.3390/ 

Andreatta G, Broyart C, Borghgraef C, Vadiwala K, Kozin V, Polo A, Bileck A, Beets I, Schoofs L, Gerner C, Raible F. Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1097-1106. doi: 10.1073/pnas.1910262116. Epub 2019 Dec 16. PMID: 31843923 Free PMC Article

Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, Crncec I, Kramer N, Unger C, Hengstschläger M, Eferl R, Moriggl R, Sommergruber W, Gerner C, Dolznig H. Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer. Angiogenesis. 2020 May;23(2):159-177. doi: 10.1007/s10456-019-09688-8; Epub 2019 Oct 30. PMID: 31667643

Kulterer OC, Niederstaetter L, Herz CT, Haug AR, Bileck A, Pils D, Kautzky-Willer A, Gerner C, Kiefer FW. The Presence of Active Brown Adipose Tissue Determines Cold-Induced Energy Expenditure and Oxylipin Profiles in Humans. J Clin Endocrinol Metab. 2020 Jul 1;105(7):dgaa183. doi: 10.1210/clinem/dgaa183. PMID: 32343312

Reichl B, Niederstaetter L, Boegl T, Neuditschko B, Bileck A, Gojo J, Buchberger W, Peyrl A, Gerner C. Determination of a Tumor-Promoting Microenvironment in Recurrent Medulloblastoma: A Multi-Omics Study of Cerebrospinal Fluid. Cancers (Basel). 2020 May 26;12(6):E1350. doi: 10.3390/cancers12061350. PMID: 32466393

Del Favero G, Mayer RM, Dellafiora L, Janker L, Niederstaetter L, Dall'Asta C, Gerner C, Marko D. Structural Similarity with Cholesterol Reveals Crucial Insights into Mechanisms Sustaining the Immunomodulatory Activity of the Mycotoxin Alternariol. Cells. 2020 Mar 31;9(4):847. doi: 10.3390/cells9040847. PMID: 32244540

Englinger B, Laemmerer A, Moser P, Kallus S, Röhrl C, Pirker C, Baier D, Mohr T, Niederstaetter L, Meier-Menches SM, Gerner C, Gabler L, Gojo J, Timelthaler G, Senkiv J, Jäger W, Kowol CR, Heffeter P, Berger W. Lipid Droplet-Mediated Scavenging As Novel Intrinsic And Adaptive Resistance Factor Against The Multikinase Inhibitor Ponatinib. Int J Cancer. 2020 Feb 16. doi: 10.1002/ijc.32924 [Epub ahead of print] PMID: 32064608

Distelmaier K, Muqaku B, Wurm R, Arfsten H, Seidel S, Kovacs GG, Mayer RL, Szekeres T, Wallisch C, Hubner P, Goliasch G, Heinze G, Heinz G, Sterz F, Gerner C, Adlbrecht C. Proteomics-Enriched Prediction Model for Poor Neurologic Outcome in Cardiac Arrest Survivors. Crit Care Med. 2020 Feb;48(2):167-175. doi: 10.1097/CCM.0000000000004105 PMID: 31939784

Muqaku, B., Pils, D., Mader, J. C., Aust, S., Mangold, A., Muqaku, L., Slany, A., Del Favero, G., & Gerner, C. (2020). Neutrophil Extracellular Trap Formation Correlates with Favorable Overall Survival in High Grade Ovarian Cancer. Cancers (Basel), 2020 Feb 21;12(2). pii: E505. doi: 10.3390/cancers12020505

Neuditschko B, Janker L, Niederstaetter L, Brunmair J, Krivanek K, Izraely S, Sagi-Assif O, Meshel T, Keppler B, Del Favero G, Witz IP, Gerner C. The challenge of classifying metastatic cell properties by molecular profiling exemplified with cutaneous melanoma cells and their cerebral metastasis from patient derived mouse xenografts. Mol Cell Proteomics. 2020 Mar;19(3):478-489. doi: 10.1074/mcp.RA119.001886. Epub 2019 Dec 31. PMID: 31892524

2019

Heudobler D, Lüke F, Vogelhuber M, Klobuch S, Pukrop T, Herr W, Gerner C, Pantziarka P, Ghibelli L, Reichle A. Anakoinosis: Correcting Aberrant Homeostasis of Cancer Tissue-Going Beyond Apoptosis Induction. Front Oncol. 2019 Dec 20;9:1408. doi: 10.3389/fonc.2019.01408. eCollection 2019. Review. PMID: 31921665

Gerner C, Costigliola V, Golubnitschaja O. MULTIOMIC patterns in body fluids: Technological challenge with a great potential to implement the advanced paradigm of 3P medicine. Mass Spectrom Rev. 2019 Nov 18. doi: 10.1002/mas.21612. [Epub ahead of print] Review. PMID: 31737933

Paulitschke V, Eichhoff O, Gerner C, Paulitschke P, Bileck A, Mohr T, Cheng PF, Leitner A, Guenova E, Saulite I, Freiberger SN, Irmisch A, Knapp B, Zila N, Chatziisaak TP, Stephan J, Mangana J, Kunstfeld R, Pehamberger H, Aebersold R, Dummer R, Levesque MP. Proteomic identification of a marker signature for MAPKi resistance in melanoma. EMBO J. 2019 Aug 1;38(15):e95874. doi: 10.15252/embj.201695874. Epub 2019 Jun 26. PMID: 31267558

Andreatta G, Broyart C, Borghgraef C, Vadiwala K, Kozin V, Polo A, Bileck A, Beets I, Schoofs L, Gerner C, Raible F. Corazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis Proc Natl Acad Sci U S A. 2019 Dec 16. pii: 201910262. doi: 10.1073/pnas.1910262116. [Epub ahead of print] PMID: 31843923

Freerk van Dijk, Naomi Teekamp, Eduard Post, Detlef B. Schuppan, Yongook O. Kim, Johan Zuidema, Rob Steendam, Matthias H.M. Klose, Samuel M. Meier-Menches, Angela Casini, Peter L. Horvatovich, Niels J. Sijbrandi, H.W. Frijlink, Wouter L.J. Hinrichs, Klaas Poelstra, Leonie Beljaars and Peter Olinga The Antifibrotic Potential of a Sustained Release Formulation of a PDGFβ-Receptor Targeted Rho Kinase Inhibitor Journal of Controlled Release, 2019, 296, 250–257

Del Favero G, Woelflingseder L, Janker L, Neuditschko B, Seriani S, Gallina P, Sbaizero O, Gerner C, Marko D. Deoxynivalenol induces structural alterations in epidermoid carcinoma cells A431 and impairs the response to biomechanical stimulation. Sci Rep. 2018 Jul 27;8(1):11351. doi: 10.1038/s41598-018-29728-5. PMID: 30054545 [PubMed - indexed for MEDLINE] Free PMC Article

Unterleuthner D, Neuhold P, Schwarz K, Janker L, Neuditschko B, Nivarthi H, Crncec I, Kramer N, Unger C, Hengstschläger M, Eferl R, Moriggl R, Sommergruber W, Gerner C, Dolznig H. Cancer-associated fibroblast-derived WNT2 increases tumor angiogenesis in colon cancer. Angiogenesis. 2019 Oct 30. doi: 10.1007/s10456-019-09688-8. [Epub ahead of print] PMID: 31667643

Gerner, MC, Niederstätter, L, Ziegler, L, Bileck, A, Slany, A, Janker, L, Schmidt, RLJ, Gerner, C, Del Favero, G & Schmetterer, KG 2019, 'Proteome Analysis Reveals Distinct Mitochondrial Functions Linked to Interferon Response Patterns in Activated CD4+and CD8+T Cells', Frontiers in Pharmacology, Jg. 10, 727. doi.org/10.3389/fphar.2019.00727

Dominique Kreutz, Christopher Gerner and Samuel M. Meier-Menches Book Chapter 10: Enabling Methods to Elucidate the Effects of Metal-based Anticancer Agents in Metallabiology Series: Metal-based Anticancer Agents, Edited by: Angela Casini, Anne Vessières and Samuel M. Meier-Menches, 2019, RSC, 356 pages, ISBN: 9781788014069.

Schenk S, Bannister SC, Sedlazeck FJ, Anrather D, Minh BQ, Bileck A, Markus H, von Haeseler A, Gerner C, Raible F, Tessmar-Raible K. Combined transcriptome and proteome profiling reveals specific molecular brain signatures for sex, maturation and circalunar clock phase. Elife. 2019 Feb 15;8. pii: e41556. doi: 10.7554/eLife.41556. PMID: 30767890

Meier-Menches SM, Zappe K, Bileck A, Kreutz D, Tahir A, Cichna-Markl M, Gerner C. Time-dependent shotgun proteomics revealed distinct effects of an organoruthenium prodrug and its activation product on colon carcinoma cells. Metallomics. 2018 Aug 14. doi: 10.1039/c8mt00152a. PMID:30106070

Janker L, Mayer RL, Bileck A, Kreutz D, Mader JC, Utpatel K, Heudobler D, Agis H, Gerner C, Slany A. Metabolic, Anti-apoptotic and Immune Evasion Strategies of Primary Human Myeloma Cells Indicate Adaptations to Hypoxia. Mol Cell Proteomics. 2019 May; 18(5):936-953. doi: 10.1074/mcp.RA119.001390. PMID: 30792264

Prosenz J, Öhlinger T, Müllner EW, Marculescu R, Gerner C, Salzer U, Kiefer FW, Baron DM. Glycated hemoglobin concentrations of red blood cells minimally increase during storage under standard blood banking conditions. Transfusion. 2019 Feb;59(2):454-457. doi: 10.1111/trf.14956. Epub 2018 Oct 1. PMID: 30727042

Bekos C, Muqaku B, Dekan S, Horvat R, Polterauer S, Gerner C, Aust S, Pils D. NECTIN4 (PVRL4) as Putative Therapeutic Target for a Specific Subtype of High Grade Serous Ovarian Cancer-An Integrative Multi-Omics Approach. Cancers (Basel). 2019 May 20;11(5). pii: E698. doi: 10.3390/cancers11050698. PMID: 31137558 [PubMed]

2018

Heudobler D, Rechenmacher M, Lüke F, Vogelhuber M, Pukrop T, Herr W, Ghibelli L, Gerner C, Reichle A. Peroxisome Proliferator-Activated Receptors (PPAR)γ Agonists as Master Modulators of Tumor Tissue. Int J Mol Sci. 2018 Nov 9;19(11). pii: E3540. doi: 10.3390/ijms19113540. Review. PMID: 30424016

Heudobler D, Rechenmacher M, Lüke F, Vogelhuber M, Klobuch S, Thomas S, Pukrop T, Hackl C, Herr W, Ghibelli L, Gerner C, Reichle A. Clinical Efficacy of a Novel Therapeutic Principle, Anakoinosis. Front Pharmacol. 2018 Nov 28;9:1357. doi: 10.3389/fphar.2018.01357. eCollection 2018. Review. PMID: 30546308

Dominique Kreutz, Chomdao Sinthuvanich, Andrea Bileck, Lukas Janker, Besnik Muqaku, Astrid Slany, Christopher Gerner Curcumin exerts its antitumor effects in a context dependent fashion Journal of Proteomics, Available online 9 May 2018, ISSN 1874-3919, doi.org/10.1016/j.jprot.2018.05.007.

Matthias H. M. Klose, Sarah Theiner, Hristo P. Varbanov, Doris Hoefer, Verena Pichler, Markus Galanski, Samuel M. Meier-Menches and Bernhard K. Keppler Development and Validation of Liquid Chromatography-Based Methods to Assess the Lipophilicity of Cytotoxic Platinum(IV) Complexes Inorganics, 2018, 6, 130.

Al-Serori H, Ferk F, Kundi M, Bileck A, Gerner C, Mišík M, Nersesyan A, Waldherr M, Murbach M, Lah TT, Herold-Mende C, Collins AR, Knasmüller S. Mobile phone specific electromagnetic fields induce transient DNA damage and nucleotide excision repair in serum-deprived human glioblastoma cells. PLoS One. 2018 Apr 12;13(4):e0193677. doi: 10.1371/journal.pone.0193677. eCollection 2018. PMID: 29649215

Kreutz D, Sinthuvanich C, Bileck A, Janker L, Muqaku B, Slany A, Gerner C. Curcumin exerts its antitumor effects in a context dependent fashion. J Proteomics. 2018 Jun 30;182:65-72. pii: S1874-3919(18)30209-4. doi: 10.1016/j.jprot.2018.05.007. Epub PMID: 29751106

Oikonomidi I, Burbridge E, Cavadas M, Sullivan G, Collis B, Naegele H, Clancy D, Brezinova J, Hu T, Bileck A, Gerner C, Bolado A, von Kriegsheim A, Martin SJ, Steinberg F, Strisovsky K, Adrain C. iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE. Elife. 2018 Jun 13;7. pii: e35032. doi: 10.7554/eLife.35032. PMID: 29897333

Cavadas M, Oikonomidi I, Gaspar CJ, Burbridge E, Badenes M, Félix I, Bolado A, Hu T, Bileck A, Gerner C, Domingos PM, von Kriegsheim A, Adrain C. Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE. Cell Rep. 2017 Oct 17;21(3):745-757. doi: 10.1016/j.celrep.2017.09.074. PMID: 29045841 [PubMed - indexed for MEDLINE]

Ribitsch I, Mayer RL, Egerbacher M, Gabner S, Kańduła MM, Rosser J, Haltmayer E, Auer U, Gültekin S, Huber J, Bileck A, Kreil DP, Gerner C, Jenner F. Fetal articular cartilage regeneration versus adult fibrocartilaginous repair: secretome proteomics unravels molecular mechanisms in an ovine model. Dis Model Mech. 2018 Jul 6;11(7). pii: dmm033092. doi: 10.1242/dmm.033092. PMID: 29991479

Zila N, Bileck A, Muqaku B, Janker L, Eichhoff OM, Cheng PF, Dummer R, Levesque MP, Gerner C, Paulitschke V. Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases. Clin Proteomics. 2018 Mar 9;15:13. doi: 10.1186/s12014-018-9189-x. eCollection 2018. PMID: 29541007 [PubMed] Free Article

Meier-Menches SM, Gerner C, Berger W, Hartinger CG, Keppler BK. Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development. Chem Soc Rev. 2018 Feb 5;47(3):909-928. doi: 10.1039/c7cs00332c. Review. PMID: 29170783 [PubMed - indexed for MEDLINE]

Lemberger UJ, Fuchs CD, Schöfer C, Bileck A, Gerner C, Stojakovic T, Taketo MM, Trauner M, Egger G, Österreicher CH. Hepatocyte specific expression of an oncogenic variant of β-catenin results in lethal metabolic dysfunction in mice. Accepted for publication in Oncotarget, 2018

Lemke A, Ferguson J, Gross K, Penzenstadler C, Bradl M, Mayer RL, Gerner C, Redl H, Wolbank S. Transplantation of human amnion prevents recurring adhesions and ameliorates fibrosis in a rat model of sciatic nerve scarring. Acta Biomater. 2018 Jan 15;66:335-349. doi: 10.1016/j.actbio.2017.11.042. Epub 2017 Nov 28. PMID: 29191510

2017

Mayer RL, Schwarzmeier JD, Gerner MC, Bileck A, Mader JC, Meier-Menches SM, Gerner SM, Schmetterer KG, Pukrop T, Reichle A, Slany A, Gerner C. Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia. Mol Cell Proteomics. 2017 Dec 1. pii: mcp.RA117.000425. doi: 10.1074/mcp.RA117.000425. [Epub ahead of print]

Cavadas, M., Oikonomidi, I., Gaspar, C. J., Burbridge, E., Badenes, M., Félix, I., Bolado A., Hu T., Bileck A., Gerner C., Domingos PM., von Kriegsheim A., Adrain C. Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE. Cell Reports, 21(3), 745-757. doi: 10.1016/j.celrep.2017.09.074

Lajkó, G., Grecsó, N., Megyesi, R., Forró, E., Fülöp, F., Wolrab, D., Lindner, W., Péter, A., & Ilisz, I. (2016). Enantioseparation of ß-carboline derivatives on polysaccharide- and strong cation exchanger-based chiral stationary phases. A comparative study. Journal of Chromatography A, 1467, 188-198. doi: 10.1016/j.chroma.2016.05.040

Schwarzer, R., Kivaranovic, D., Mandorfer, M., Paternostro, R., Wolrab, D., Heinisch, B., Reiberger, T., Ferlitsch, M., Gerner, C., Trauner, M., Peck-Radosavljevic, M., & Ferlitsch, A. (2017). Randomised clinical study: The effects of oral taurine 6/day g vs placebo daily on portal hypertension. Alimentary Pharmacology and Therapeutics. doi: 10.1111/apt.14377

Meier-Menches SM, Gerner C, Berger W, Hartinger CG, Keppler BK. Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development. Chem Soc Rev. 2017 Nov 24. doi: 10.1039/c7cs00332c. [Epub ahead of print] Review.

Bileck, A., Mayer, R. L., Kreutz, D., Weiss, T., Taschner-Mandl, S., Meier, S. M., . . . Gerner, C. Evaluation of inflammation-related signaling events covering phosphorylation and nuclear translocation of proteins based on mass spectrometry data. J Proteomics, 152, 161-171. doi: 10.1016/j.jprot.2016.11.008

Muqaku B, Eisinger M, Meier SM, Tahir A, Prokop T, Haferkamp S, Slany A, Reichle A, Gerner C. Multi-omics analysis of serum samples demonstrates reprogramming of organ functions via systemic calcium mobilization and platelet activation in metastatic melanoma. Mol Cell Proteomics, 16(1), 86-99. doi: 10.1074/mcp.M116.063313

Kreutz D, Bileck A, Plessl K, Wolrab D, Groessl M, Keppler BK, Meier SM, Gerner C. Response Profiling Using Shotgun Proteomics Enables Establishing Global Metallodrug Mechanisms of Action. Chemistry – A European Journal, 23(8), 1881-1890. doi: 10.1002/chem.201604516

Wolrab, D., Fruhauf, P., Gerner, C., Kohout, M., & Lindner, W. Consequences of transition from liquid chromatography to supercritical fluid chromatography on the overall performance of a chiral zwitterionic ion-exchanger. J Chromatogr A. 1517, 165-175, doi: 10.1016/j.chroma.2017.08.022

Kral, M., Klimek, C., Kutay, B., Timelthaler, G., Lendl, T., Neuditschko, B., . . . Csiszar, A. Covalent Dimerization of Interleukin-Like Epithelial-to-Mesenchymal Transition (EMT) Inducer (ILEI) Facilitates EMT, Invasion and Late Aspects of Metastasis. FEBS J. 2017 Oct;284(20):3484-3505. doi: 10.1111/febs.14207. Epub 2017 Sep 14.

Drev, D., Bileck, A., Erdem, Z. N., Mohr, T., Timelthaler, G., Beer, A., Gerner, C., Marian, B. Proteomic profiling identifies markers for inflammation-related tumor-fibroblast interaction. Clin Proteomics. 2017 Oct 6;14:33. doi: 10.1186/s12014-017-9168-7. eCollection 2017

Wolrab D, Frühauf P, Gerner C. Direct coupling of supercritical fluid chromatography with tandem mass spectrometry for the analysis of amino acids and related compounds: Comparing electrospray ionization and atmospheric pressure chemical ionization. Anal Chim Acta. 2017 Aug 15;981:106-115. doi: dx.doi.org/10.1016/j.aca.2017.05.005. Epub 2017 May 15. PMID: 28693724 [PubMed - in process]

Schoenhacker-Alte B, Mohr T, Pirker C, Kryeziu K, Kuhn PS, Buck A, Hofmann T, Gerner C, Hermann G, Koellensperger G, Keppler BK, Berger W, Heffeter P. Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis. Cancer Letters, 404, 79-88. doi: dx.doi.org/10.1016/j.canlet.2017.07.009

Mohr, T., Haudek-Prinz, V., Slany, A., Grillari, J., Micksche, M., & Gerner, C. Proteome profiling in IL-1beta and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis. PLoS One, 12(6), e0179065. doi: 10.1371/journal.pone.0179065

Bachmayr-Heyda, A., Aust, S., Auer, K., Meier, S. M., Schmetterer, K. G., Dekan, S., Gerner, C. & Pils, D. Integrative Systemic and Local Metabolomics with Impact on Survival in High-Grade Serous Ovarian Cancer. Clinical Cancer Research, 23(8), 2081-2092. doi: 10.1158/1078-0432.ccr-16-1647

Sommerfeld, N. S., Hejl, M., Klose, M. H. M., Schreiber-Brynzak, E., Bileck, A., Meier, S. M., Gerner, C., Jakupec, M. A., Galanski, M. & Keppler, B. K. Low-Generation Polyamidoamine Dendrimers as Drug Carriers for Platinum(IV) Complexes. European Journal of Inorganic Chemistry. 12, S. 1713-1720 8 S.

Samuel M. Meier, Dominique Kreutz, Lilli Winter, Matthias H.M. Klose, Klaudia Cseh, Tamara Weiss, Andrea Bileck, Beatrix Alte, Johanna C. Mader, Samir Jana, Annesha Chatterjee, Arindam Bhattacharyya, Michaela Hejl, Michael A. Jakupec, Petra Heffeter, Walter Berger, Christian G. Hartinger, Bernhard K. Keppler, Gerhard Wiche and Christopher Gerner. An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin. Angew Chem Int Ed 2017, 56, 8299

Aust S, Felix S, Auer K, Bachmayr-Heyda A, Kenner L, Dekan S, Meier SM, Gerner C, Grimm C, Pils D. Absence of PD-L1 on tumor cells is associated with reduced MHC I expression and PD-L1 expression increases in recurrent serous ovarian cancer. Sci Rep. 2017 Mar 7;7:42929.

Hochkogler CM, Lieder B, Rust P, Berry D, Meier SM, Pignitter M, Riva A, Leitinger A, Bruk, A Wagner S, Hans J, Widder S, Ley JP, Krammer GE, Somoza V. A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects. Mol Nutr Food Res. 2016 Dec 24.

Tahir A, Bileck A, Muqaku B, Niederstaetter L,Kreutz D, Mayer RL, Wolrab D, Meier SM, Slany A, Gerner C. Combined proteome and eicosanoid profiling reveals novel implications of human fibroblasts in chronic inflammation. Anal Chem. 2017 89 (3), 1945-1954 doi: http://dx.doi.org/10.1021/acs.analchem.6b04433

2016

Schenk S, Krauditsch C, Frühauf P, Gerner C, Raible F. Discovery of methylfarnesoate as the annelid brain hormone reveals an ancient role of sesquiterpenoids in reproduction. Elife. 2016 Nov 29;5. pii: e17126. doi: 10.7554/eLife.17126.

Auer K, Bachmayr-Heyda A, Sukhbaatar N, Aust S, Schmetterer KG, Meier SM, Gerner C, Grimm C, Horvat R, Pils D. Role of the immune system in the peritoneal tumor spread of high grade serous ovarian cancer. Oncotarget. 2016 [Epub ahead of print]

Bachmayr-Heyda A, Aust S, Auer K, Meier SM, Schmetterer KG, Dekan S, Gerner C, Pils D. Integrative Systemic and Local Metabolomics with Impact on Survival in High Grade Serous Ovarian Cancer. Clin Cancer Res. 2016 [Epub ahead of print]

Sommerfeld NS, Schreiber-Brynzak E, Klose M, Bileck A, Meier SM, Gerner C, Jakupec MA, Galanski M, Keppler BK. Low generation PAMAM dendrimers as drug carriers for Pt(IV) complexes. EUrJIC. 2016 [Epub ahead of print]

Weiss T, Taschner-Mandl S, Bileck A, Slany A, Kromp F, Rifatbegovic F, Frech C, Windhager R, Kitzinger H, Tzou CH, Ambros PF, Gerner C, Ambros IM. Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype. Glia. 2016 Aug 22

Putz EM, Majoros A, Gotthardt D, Prchal-Murphy M, Zebedin-Brandl EM, Fux Da, Schlattl A, Schreiber RD, Carotta S, Müller M, Gerner C, Decker T, Sexl V. Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity. OncoImmunology. 2016 Sep 1

Wolrab D, Frühauf P, Gerner C. Quantification of the neurotransmitter melatonin and N-acetyl-serotonin in human serum by supercritical fluid chromatography coupled with tandem mass spectrometry. Anal Chim Acta 2016 [Epub ahead of print]

Muqaku B, Tahir A, Klepeisz P, Bileck A, Kreutz D, Mayer RL, Meier SM, Gerner M, Schmetterer K, Gerner C. Coffee consumption modulates inflammatory processes in an individual fashion. Mol Nutr Food Res. 2016 [Epub ahead of print]

Conibear AC, Farbiarz K, Mayer RL, Matveenko M, Kaehlig H, Becker CF. Arginine side-chain modification that occurs during copper-catalysed azide-alkyne click reactions resembles an advanced glycation end product. Org Biomol Chem. 2016 [Epub ahead of print]

Meshcheryakova A, Svoboda M, Tahir A, Köfeler HC, Triebl A, Mungenast F, Heinze G, Gerner C, Zimmermann P, Jaritz M, Mechtcheriakova D. Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach. Oncotarget. 2016 Mar 7. [Epub ahead of print]

Slany A, Bileck A, Kreutz D, Mayer RL, Muqaku B, Gerner C. Contribution of human fibroblasts and endothelial cells to the Hallmarks of Inflammation as determined by proteome profiling. Mol Cell Proteomics. 2016 Mar 29. [Epub ahead of print]

Gschwandtner M, Paulitschke V, Mildner M, Brunner PM, Hacker S, Eisenwort G, Sperr WR, Valent P, Gerner C, Tschachler E. Proteome-analysis identifies L1CAM / CD171 and DPP4 / CD26 as novel markers of human skin mast cells. Allergy: European Journal of Allergy and Clinical Immunology, 72(1), 85-97. doi: 10.1111/all.12919. Epub 2016 May 25.

Šmidák R, Mayer RL, Bileck A, Gerner C, Mechtcheriakova D, Stork O, Lubec G, Li L. Quantitative proteomics reveals protein kinases and phosphatases in the individual phases of contextual fear conditioning in the C57BL/6J mouse. Behav Brain Res. 2015 Dec 31;303:208-217

Wolrab D, Frühauf P, Moulisová A, Kuchař M, Gerner C, Lindner W, Kohout M. Chiral separation of new designer drugs (Cathinones) on chiral ion-exchange type stationary phases. J Pharm Biomed Anal. 2016 Feb 20;120:306-15.

Meier SM, Gerner C, Keppler BK, Cinellu MA, Casini A. Mass Spectrometry Uncovers Molecular Reactivities of Coordination and Organometallic Gold(III) Drug Candidates in Competitive Experiments That Correlate with Their Biological Effects. Inorg Chem. 2016 Feb 11. [Epub ahead of print]

2015

Meier SM, Muqaku B, Ullmann R, Bileck A, Kreutz D, Mader JC, Knasmüller S, Gerner C. Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor Racemosus Secondary Metabolites Compared to Dexamethasone. PLoS One. 2015 Oct 23

Slany A, Bileck A, Muqaku B, Gerner C. Targeting breast cancer-associated fibroblasts to improve anti-cancer therapy. Breast. 2015 [Epub ahead of print]

Bileck A, Ferk F, Al-Serori H, Koller VJ, Muqaku B, Haslberger A, Auwärter V, Gerner C, Knasmüller S. Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage. Arch Toxicol 2015 [Epub ahead of print]

Muqaku B, Slany A, Bileck A, Kreutz D, Gerner C. Quantification of cytokines secreted by primary human cells using MRM: evaluation of analytical parameters. Anal Bioanal Chem. 2015 [Epub ahead of print]

Karlic H, Thaler R, Gerner C, Grunt T, Proestling K, Haider F, Varga F. Inhibition of the mevalonate pathway affects epigenetic regulation in cancer cells. Cancer Genet. 2015 Mar 18 [Epub ahead of print]

Kaintz C, Mayer RL, Jirsa F, Halbwirth H, Rompel A. Site-directed mutagenesis around the CuA site of a polyphenol oxidase from Coreopsis grandiflora (cgAUS1). FEBS Lett. 2015 Feb 16 [Epub ahead of print]

Molitor C, Mauracher SG, Pargan S, Mayer RL, Halbwirth H, Rompel A Latent and active aurone synthase from petals of C. grandiflora: a polyphenol oxidase with unique characteristics Planta. 2015 Feb 20 [Epub ahead of print]

Paulitschke V, Berger W, Paulitscjke P, Hofstaetter E, Knapp B, Dingelmaier-Hovorka, Födinger D, Jäger W, Szekeres T, Meshcheryakova A, Bileck A, Pirker C, Pehamberger H, Gerner C, Kunstfeld R Vemurafenib resistance signature by proteome analysis offers new strategies and rational therapeutic concepts Mol Cancer Ther. 2015 Jan 22 [Epub ahead of print]

2014

Baron DM, Kaindl U, Haudek-Prinz VJ, Bayer E, Röhrl C, Gerner C, Marian B. Autonomous inhibition of apoptosis correlates with responsiveness of colon carcinoma cell lines to ciglitazone. PLoS One. 2014 Dec 11;9(12).

Bileck A, Kreutz D, Muqaku B, Slany A, Gerner C. Comprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells. J Proteome Res. 2014 Dec 5;13(12):5989-6000.

Paulitschke V, Gerner C, Hofstätter E, Mohr T, Mayer R, Pehamberger H, Kunstfeld R Proteome profiling of keratinocytes transforming to malignancy. Electrophoresis. 2014 Nov 14. [Epub ahead of print]

Veitinger M, Oehler R, Umlauf E, Baumgartner R, Schmidt G, Gerner C, Babeluk R, Attems J, Mitulovic G, Rappold E, Lamont J, Zellner M. A platelet protein biochip rapidly detects an Alzheimer's disease-specific phenotype. Acta Neuropathol. 2014 Nov;128(5):665-77.

Groessl M, Slany A, Bileck A, Gloessmann K, Kreutz D, Jaeger W, Pfeiler G, Gerner C. Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts. J Proteome Res. 2014 Nov 7;13(11):4773-82.

Slany A, Meshcheryakova A, Beer A, Ankersmit HJ, Paulitschke V and Gerner C Plasticity of fibroblasts demonstrated by tissue-specific and function-related proteome profiling Clinical Proteomics 2014, 11:41

Slany A, Paulitschke V, Haudek-Prinz V, Meshcheryakova A, Gerner C. Determination of cell type-specific proteome signatures of primary human leukocytes, endothelial cells, keratinocytes, hepatocytes, fibroblasts and melanocytes by comparative proteome profiling. Electrophoresis 2014, 35:1428-38.

Zekiri F, Molitor C, Mauracher SG, Michael C, Mayer RL, Gerner C, Rompel A. Purification and characterization of tyrosinase from walnut leaves (Juglans regia). Phytochemistry. 2014, 101:5-15.

Falsafi SK, Roßner S, Ghafari M, Groessl M, Morawski M, Gerner C, Lubec G. Changes of several brain receptor complexes in the cerebral cortex of patients with Alzheimer disease: probable new potential pharmaceutical targets. Amino Acids. 2014, 46:223-33

Slany A, Haudek-Prinz V, Meshcheryakova A, Bileck A, Lamm W, Zielinski C, Gerner C, Drach J. Extracellular matrix remodeling by bone marrow fibroblast-like cells correlates with disease progression in multiple myeloma. J Proteome Res. 2014, 13:844-54

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